CNS Goals

The primary goals of the Clinical Neuroscience Laboratory at Yale University are to elucidate genetic, neural, and behavioral mechanisms underlying psychotic forms of mental illness – principally schizophrenia and bipolar disorder – and to develop effective intervention and prevention strategies targeting these mechanisms. Our approaches include structural, functional and metabolic brain imaging, neurocognitive assessment, and quantitative and molecular genetics. These approaches are applied in the context of twin studies, longitudinal developmental studies, birth cohort studies, and randomized, controlled trials.

See these links for summaries of our findings related to the genetics and neuroscience of schizophrenia and bipolar disorder and to the prediction and prevention of psychosis.

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